At least four people have died in Niger in violent protests over the Charlie Hebdo's publication of a new cartoon of the Prophet Mohammed.
Forty five people were also injured in the clashes in Nigeria's second city of Ziner, with demonstrators ransacking three churches and setting fire to the French cultural centre.
Three people were injured when protesters clashes with police outside the French consulate in Karachi, Pakistan.
Protesters in Senegal and Mauritania torched French flags, and Qatar and Bahrain warned that the cartoon could fuel hatred.
Thousands of people around the world have been taking to the streets to vent anger at the French satirical magazine's new cartoon, which features the prophet holding a Je Suis Charlie sign under the headline "All Is Forgiven".
In Pakistan, police fired water cannon and tear gas into the air as they clashed with protesters from the Jamaat-e-Islami religious party.
The nationwide rallies followed comments by Prime Minister Nawaz Sharif, who led parliament in condemning the cartoons in Charlie Hebdo, whose Paris offices were attacked last week, leaving 12 people dead.
A statement from one faction of the Pakistani Taliban, meanwhile, issued a statement lauding the two brothers who carried out the massacre, saying: "They freed the earth from the existence of filthy blasphemers".
Insulting the Prophet carries the death penalty under Pakistan's blasphemy laws, with 14 people currently on death row.
In Amman, around 2,500 protesters set off from Al-Husseini mosque under tight security, holding banners that read "insulting the prophet is global terrorism".
In Algiers, there were clashes as up to 3,000 marchers chanted "We are all Mohammed". Some shouted support for the Islamist Kouachi brothers, who carried out the Charlie Hebdo murders.
Around 100 protesters rallied in Istanbul in response to a call by a group calling itself the Fraternal Platform of the Prophet's Companions, with some holding pictures of the Kouachis.
This man protested in the Algerian capital, Algiers.