Heineken is being pulled from all of JD Wetherspoon's 926 pubs in the UK and Ireland after an argument about supplying its lager and Murphy's stout to the chain's new pub in Dún Laoghaire, Co Dublin.
Wetherspoon's has been working with the company for over 35 years and their contract is thought to be worth £60m (€76m). Heineken is Ireland's most popular draft lager.
Reuters reports that the row centred around pricing while Wetherspoon's has said that the brewery demanded personal guarantees from its chief executive, John Hutson in order to supply products to the second Irish outlet.
The company currently sells Heineken and Murphy's in their other Irish pub, The Three Tun Tavern in Blackrock, Co Dublin. Both have been retailing at €2.95, well below Dublin averages of €5.
This is Wetherspoon's second disagreement with a drinks company since coming to Ireland. Previously the company fell out with Diageo over the price it charged for Guinness. The bar decided not to stock the porter, which accounts for one out of every three pints sold in Ireland.
Wetherspoon's has previously indicated that it intends to open around 30 pubs in the Republic. The Forty Foot in Dún Laoghaire is its second Irish bar, due to open next Tuesday, December 16th.
The company has also secured locations in the Dublin suburbs of Swords and Blanchardstown, as well as one in Cork City.