Adi Roche is to receive the Freedom of Cork City for her work with Chernobyl Children International (CCI).
The campaigner has been at the forefront of efforts to support the people of Chernobyl since one of the world's worst nuclear disaster in April 1986. She founded the CCI charity in 1991.
The voluntary CEO of the charity has said being awarded the Freedom of the City will be one of her "proudest moments", adding that Cork is her "favourite city".
Ms Roche said, “it is a great honour and privilege to be honoured by Cork City Council. I will be proud to accept the Freedom of the City on behalf of myself and all our wonderful volunteers, staff and donors and on behalf of all the innocent victims of Chernobyl especially the children”.
Previous recipients of the Freedom of Cork City include Mary Robinson, Eamon de Valera, Mary McAleese and John Hume.
Lord Mayor and Chief Executive of Cork City Council, Ann Doherty - who travellled to Belarus with Ms Roche earlier this year - said, "I was delighted to travel to the Ukraine in February to witness at first hand the tremendous work being carried out by the charity and the volunteers.
"It is the only non-government aid organisation in Chernobyl recognised by the United Nations and has become the largest global contributor to victims of the Chernobyl disaster in Belarus," the Lord Mayor added.