UK Labour leader Jeremy Corbyn has confirmed his party will back a second Brexit referendum to avoid a no-deal Brexit.
However, he stressed the party will also continue to push for "other available options".
It comes after MPs rejected Labour's alternative plan for Brexit by 323 votes to 240.
Mr Corbyn's party is calling for the UK to join a customs union with the EU after Brexit.
Another defeat for that proposal means party policy shifts towards supporting a second Brexit referendum, with staying in the EU potentially among the options.
Labour members have previously voted to campaign for a second referendum if they can't secure their preferred outcome - a general election.
Responding to tonight's House of Commons vote, Mr Corbyn said: “We will back a public vote in order to prevent a damaging Tory Brexit or a disastrous no deal outcome.
“We will also continue to push for the other available options to prevent those outcomes, including a close economic relationship based on our credible alternative plan or a general election.”
The House of Commons this evening also voted against an amendment by the Scottish National Party calling for the UK to avoid a no-deal exit in all circumstances.
Key Brexit votes
Meanwhile, MPs voted by 502 to 20 to back a motion from Labour MP Yvette Cooper's to guarantee key votes promised by Theresa May in two weeks.
Only a small group of pro-Brexit Conservatives voted against it.
Yesterday, Mrs May said MPs will be offered another "meaningful vote" on the proposed withdrawal deal and any changes secured with the EU on March 12th "at the latest."
If that fails, a vote on whether the House of Commons supports leaving the EU without a deal will be held on March 13th.
Should that also be rejected, MPs will be offered a March 14th vote on a "short, limited" extension to the Brexit process.
Any such Article 50 extension would need to be agreed with the EU.
Key leaders in Brussels have repeatedly ruled out the prospect of renegotiating the withdrawal deal which has already been rejected by MPs.
They've said they'll continue to offer Mrs May assurances to try and persuade MPs to support the deal, but have dismissed the prospect of any substantial changes to the Irish backstop.