There have been 54 additional deaths related to COVID-19 and 1,335 new cases reported on Wednesday.
The Health Protection Surveillance Centre (HPSC) says 50 of the deaths happened in January.
The median age of those who died is 85 years, and the age range is between 55 and 96 years.
There has been a total of 3,120 coronavirus related deaths and 191,182 confirmed cases in Ireland.
This includes the denotification of four confirmed cases.
Of the cases notified on Wednesday:
- 618 are men / 711 are women
- 54% are under 45 years of age
- The median age is 43 years old
There are 437 cases in Dublin, 114 in Cork, 78 in Galway, 71 in Meath and 61 in Louth.
The remaining 574 cases are spread across all other counties.
As of 2.00pm, 1,670 COVID-19 patients are hospitalised - of which 217 are in ICU.
There have been 81 additional hospitalisations in the past 24 hours.
Chief Medical Officer Dr Tony Holohan said: "The current 14 day incidence remains more than double the peak incidence experienced during previous level five measures in October.
"Therefore, now is not the time to drop your guard and start to interact with people outside your household.
"The risk of transmission in the community remains very high. We must continue to work towards reducing incidence of disease and preventing further hospitalisations and deaths."
The seven-day incidence stands at 249.7, while the five-day moving average is 1,383.
