There has been one further death related to COVID-19 and 269 new cases confirmed this evening by the National Public Health Emergency Team (NPHET).
The number of coronavirus-related deaths has now risen to 4,836, while the latest figures bring the total amount of cases here to 243,508.
Of the latest cases, 70% are under 45 years of age, while the median age is 31 years old.
As of 8am today, 181 people are now receiving treatment in hospital for the virus after six new admissions in the past 24 hours.
Of those patients, 47 are in ICU, down from 50 yesterday.
The five-day moving average is now 369.
As of April 16th, 1,188,354 doses of the COVID-19 vaccine have been administered in Ireland.
838,644 people have received their first dose, while a second dose has been given to 349,710 people.
Dr Ronan Glynn, Acting Chief Medical Officer at the Department of Health, said: "We have already seen the fantastic impact of vaccination amongst our healthcare workers and in our nursing homes.
"However, the declining incidence across all age groups in recent weeks cannot be attributed to vaccination but rather to the enormous efforts of people across society to keep themselves and their families safe.
“If we can keep incidence relatively low over the coming weeks, vaccination will increasingly play a role in suppressing this virus.
"This will make it easier for all of us to balance the risks associated with COVID-19 while gradually easing public health measures."
Dr Glynn urged that people continue to keep their distance and wear a mask, avoid mixing indoors with other households, work from home where at all possible, get vaccinated as soon as it's their turn, and to isolate and contact a GP to arrange a test if showing symptoms of the virus.