Police say two men and two women have been shot dead at a business in St Louis, Missouri.
KTVI-TV reports that the shooting was targeted at one particular business within the Cherokee Place Business Incubator.
Emergency crews and homicide investigators are at the scene.
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Police said they were not searching for a shooter.
Thursday's shooting comes amid a violent week for St Louis, with police there having reported 17 shootings overnight from Monday to Tuesday.