Justice Minister Helen McEntee has tested positive for COVID-19.
The minister - who recently announced she is pregnant - says health advice shows pregnant women and their babies are not at higher risk from the virus.
Minister McEntee says she will continue carrying out her duties remotely while isolating, and will attend Cabinet meetings remotely.
I was recently tested and have received a positive result for #Covid19. In line with our HSE guidance I am isolating. I am continuing to carry out my duties by working remotely including attending Cabinet.
— Helen McEntee TD (@HMcEntee) January 6, 2021
In a series of tweets, she said: "I urge everyone to follow public health advice and stay at home.
"If you think you’re developing symptoms no matter how small, act as though you have Covid.
"We all know the seriousness of the situation. We must protect our health system and our most vulnerable."
Last month, Agriculture Minister Charlie McConalogue tested positive for the virus - prompting other ministers to temporarily restrict their movements until they'd received a negative test result.
Cabinet meets today to sign-off on new restrictions, including for schools and the construction sector.