Mairead Philpott has the lost her appeal against the 17-year prison sentence imposed for the killing of her six children in the UK
There was applause in court as the verdict was read out, and a call of "you go back to prison and tell her that" was heard from the public gallery.
Earlier the court heard that Mairead Philpott was not safe in prison and her 17-year prison sentence for killing her six children was unfair.
In the most high-profile case to be broadcast since cameras were allowed into the UK Court of Appeal last month, Shaun Smith QC, representing Philpott, said she will forever be known as a "child killer".
He told the appeal court in Nottingham there had been "a clamour for the draconian punishment" for Philpott even before her sentence was passed, and added that Mairead was under the influence of her husband Mick, 56, who was jailed for life.
"Whatever happens from now on," he said, "there will be a number of permanent reminders of her inability to say stop."
"She will, despite the fact that she has been found guilty of manslaughter, be forever known as a child killer. Her time in custody will inevitably carry with it the risks attached to all inmates serving sentences involving the death of children".
"When she is released she will have no support network, nobody supports her, at all. She will never again be allowed to have children or be involved with children" he added.
Philpott (33) and family friend Paul Mosley (46) got 17 years for the manslaughter of the children in a house fire in Derby in May 2012. Mick has not appealed, and a plan for Mosley to appeal has been abandoned.
Jade Philpott (10) and her brothers, Duwayne (13), John (9), Jack (8), Jesse (6), and Jayden (5), all died in their bedrooms after a fire swept through the family home.
Mairead's father, Jimmy Duffy, earlier said she "shouldn't be appealing at all. They should be getting on with what they've got," he added.
Mr. Duffy said he was in support of court proceedings being televised.
"Basically they're going to be seen for what they are, in fact they should have televised the whole case if I had my way," he said.
Mr. Duffy said his daughter had written to him from prison.
In the letter, Philpott said she is "coping as best as I can it's hard but I'm doing ok for now", and signs off, "Hope to hear from you soon, love Mairead xxxxxx".
But Mr. Duffy has little sympathy for her.
"I love her, she's my daughter, don't get me wrong, she's my flesh and blood, but I can't forgive her for even having a part in it," he said.
Mosley's sister Angela does not think he should have tried to appeal in the first place.
She said "If you knew your friend was going to set fire to their house, my first port of call would be to the police station. You would do everything in your power to stop the fire but they didn't they carried on, they're guilty".
It is the first time in Britian a Court of Appeal hearing has been filmed outside of London.