A man in his forties is due in court in Mayo later - in connection with the murder of Sandra Collins twelve years ago.
The 29 year old was last seen in Killala on December 4th 2000.
Three people have previously been arrested in connection with her disappearance - but none were charged.
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Yesterday, Gardai arrested a man in Ballina. He's due before a special sitting of Ballina District court at 11 o'clock this morning.