An opt-out organ donation system is one step closer, after Cabinet ministers gave permission to draft new laws.
Under the new system, it would be assumed people want to become organ donors unless they state otherwise.
The Health Minister Simon Harris brought the proposals to Cabinet on Tuesday morning.
The general scheme of the bill will be published on Wednesday.
The Human Tissue Bill will give effect to a Government commitment to propose legislation for family consent and an opt-out register for organ donation.
Under this system, consent will be given unless the person has, while alive, registered their wish not to become an organ donor after death.
It is proposed that the next of kin will always be consulted before removing any organ.
A public consultation was held on the proposals back in 2017.
Speaking at the time, Minister Harris said: "Organ donation is among the most selfless acts we can bestow upon another person.
"An opt-out system of consent for organ donation and accompanying publicity campaign will raise awareness among individuals and encourage discussion among families of their intentions in relation to organ donation. In this way individuals can increase the chances that their organs might be utilised after their death, and can ensure that those left behind will have the satisfaction of knowing that their wishes were carried through."
Minister Harris also said Ireland needed to "change its attitude to organ donation", and adopt an opt-out system of consent.
"I want to see a time where organ donation is the norm when people pass away in circumstances in which donation is a possibility".
"The Human Tissue Bill will ensure that the principles of protection of the bodily integrity of the individual before and after death; respect for the autonomy of the individual and the rights of the bereaved; and promotion of the public health benefits of post-mortem examination and tissue donation are enshrined in legislation", he added.
Additional reporting: Sean Defoe