A major bridge has collapsed in the US city of Baltimore after it was hit by a cargo ship.
Footage shows a large section of the 1.6 mile-long Francis Scott Key Bridge in Maryland falling into the water following the collision at around 1.30am local time.
Baltimore's fire service said emergency teams are searching for at least seven people believed to have fallen into the water.
A major bridge has collapsed in the US city of Baltimore after it was hit by a cargo ship. pic.twitter.com/AtjbtMFMyR
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Baltimore City Fire Department Director of Communications Chief Kevin Cartwright said the main focus right now is "trying to rescue and recover these people".
He said it's too early to know how many people were affected but called the collapse a "developing mass casualty event".
Mr Cartwright said it appears there are "some cargo or retainers hanging from the bridge," creating unsafe and unstable conditions, and that emergency service workers are operating cautiously as a result.
"This is a dire emergency," he said.
Vehicles can be seen in the footage falling from the bridge.
The container ship, known as Dali, was headed to Colombo in Sri Lanka at the time of the collision. Data from MarineTraffic shows the Singapore-flagged ship stop at the bridge.
According to the data, the first ship to arrive around 10 minutes later was a tug Eric Mcallister based at the port.
It was joined by a second tug Bridget Mcallister and a search and rescue vessel around 25 minutes after the bridge was hit.
There are more than 10 boats involved in the rescue.
A spokesperson for Baltimore Police Department told NBC News that it had been notified of the incident at the Francis Scott Key Bridge.
"I can confirm at 1.35am, Baltimore City police were notified of a partial bridge collapse, with workers possibly in the water, at the Francis Scott Key Bridge," Detective Niki Fennoy said in a statement.
Baltimore's Mayor, Brandon M Scott, said emergency personnel were on the scene and rescue efforts were underway, while Johnny Olszewski, Baltimore county executive, said he remains in contact with the chief of the fire department and the director of emergency operations.
"Please pray for those impacted," Mr Olszewski said.
Built in 1977, the bridge is referred to locally as the Key Bridge. It is one of the longest continuous truss bridges in the world, according to the National Steel Bridge Alliance.
Reporting by: IRN