The Government is nominating Phil Hogan for a second term as a member of the European Commission.
The Fine Gael politician has served in Brussels as Agriculture & Rural Development Commissioner since 2014.
Work is now underway to appoint a new commission, following the nomination of German Defence Minister Ursula Von Der Leyen to be the next European Commission President.
Each member state nominates one member of the commission, with candidates then going through a vetting process by MEPs.
Confirming Ireland's nomination, Leo Varadkar said Mr Hogan has done an "excellent job" in his EU role.
The Taoiseach said: "Phil is widely respected in Brussels and across the EU as a skilled negotiator and someone who builds alliances.
"He has also been a very important voice on Brexit, ensuring that his colleagues in the Commission have a keen understanding of the potential negative impact that the UK’s exit will have on Ireland and other Member States."
The Taoiseach pointed to the recent €50 million aid package for Irish beef farmers as an example of Mr Hogan's efforts.
Mr Varadkar added: "His re-nomination is an endorsement of his work to date, and an indication of the importance we place on our engagement with EU institutions.
"The Government will now work closely with our colleagues in the EU to support him in securing the best possible portfolio in the new Commission."
The re-nomination comes despite Phil Hogan having faced criticism over the recent agreement for an EU trade deal with the South American trade bloc Merocsur, amid concerns over the potential impact on beef farmers here.
Opposition parties and farming groups criticised the deal and the Irish commissioner, while the Government also said it was "very concerned" about the potential impact of the agreement.
Mr Hogan, however, defended the deal - insisting it was "fair and balanced".
