Ryanair says more than 250 of its staff have lost their jobs across several of its bases, including Dublin.
The company said it reduced its office headcount in Dublin, London, Madrid and Wroclaw through a combination of probation/fixed term contract ends, resignations and redundancies.
The carrier said these people will not be required to return to work on June 1st, when the Ryanair offices re-open.
It added that this was due to the "substantial decline in traffic" due to the coronavirus.
Ryanair said its airlines operated less than 1% of their normal flight schedules during April, May and June.
Darrell Hughes from Ryanair said: "This is a very painful time for Ryanair, our crews and our people supporting operations from our Dublin, Stansted, Madrid and Wroclaw offices."
"These job losses were communicated to individual team members this week, and they will not be returning to work in our Dublin, Stansted, Madrid or Wroclaw offices when they reopen on June 1st next.
"We are continuing to meet our pilot and cabin crew unions across Europe to finalise up to 3,000 job cuts and 20% pay cuts as we return to approx. 40% of our normal flight schedules from July onwards."
The company said further announcements on job losses and pay cuts are expected before the end of May.