Ryanair has said it is 'severely reducing' flights to and from Spain, the Balearic Islands and Canary Islands for the next several days.
It comes as the Spanish government said the country was being put into partial lockdown, with people being asked to stay home other than going out to buying essential supplies or for work.
Spain has confirmed more than 6,000 cases of coronavirus and 196 deaths - the second highest number in Europe after Italy.
Here, the Government is currently advising against all non-essential travel to Spain.
Ryanair today said it will severely reduce flights from midnight tonight until Friday morning.
It says all affected passengers are being contacted, and urged people not to call the airline.
The company said: "This is a fast-moving and complex situation and the safety and well-being of our people and customers is our main priority.
"We will continue to comply fully with all WHO and EASA guidelines and we will follow any travel restrictions that are imposed.
"Ryanair Group Airlines apologises sincerely to all customers affected by these restrictions introduced by the Spanish Government which are necessary to combat the COVID-19 virus."
Yesterday, the company also suspended all flights to and from Poland over the coronavirus measures being put in place there.
Customer Notice: All Ryanair Group Flights to/from Poland Cancelled From Sunday 15 March To Tuesday 31 March.
Affected customers will receive an email notification informing them of their options: pic.twitter.com/0ERiMVJvWC— Ryanair (@Ryanair) March 14, 2020
As more countries introduce significant travel restrictions, Aer Lingus has asked the only passengers due to fly in the next 72 hours call the airline.
The company said: "While we have expanded our call centre and social media teams in recent days, we know that guests experiencing flight disruption are having difficulty getting through to us.
"We want to ensure that our social media and call centre teams can deal with those experiencing flight disruption and with imminent travel plans."
They said that change fees have been waived due to the current coronavirus situation.
In the wake of the US announcement yesterday that the European travel ban is being expanded to Ireland from midnight on Monday, Aer Lingus said it was assessing the situation and would "communicate directly with affected guests as soon as possible".
While flights continue to operate, it's reported that many flights are operating at low capacity as more people cancel travel plans due to the COVID-19 outbreak.
There were 237 people booked on this flight from Washington DC to Dublin. 34 got on board pic.twitter.com/XHyLSFmyiG
— Seán Defoe (@SeanDefoe) March 15, 2020
Main image: File photo of Ryanair plane at Palma de Mallorca Airport. Picture by: Clara Margais/DPA/PA Images