Pubs should be able to fully re-open from Friday night with enough notice, the Vintners' Federation of Ireland (VFI) says.
It comes after NPHET has given the green light for almost all restrictions to be lifted.
It is believed the only rules NPHET is recommending should be kept in place are the use of facemasks in certain settings and the requirement to self-isolate when symptomatic.
While Cabinet ministers will meet later to agree a timeline.
Sources left open the idea that normal trading hours for hospitality could return from Saturday, with nightclubs also opening.
If not Saturday, Monday was the other date being discussed.
While VFI chief executive Padraig Cribben told Newstalk Breakfast a full re-opening now would be in keeping with the latest public health advice.
"We have been closed now for the guts of 22 months - either closed or significantly restricted.
"We've been clear since day one... that we should follow the public health advice.
"The public health advice now would appear to be very clearly that we should be allowed fully open.
"And we believe that should happen immediately".
And he says the advice will be the same on Monday.
"There is nothing wrong with tonight if the indications are given early today.
"There is an opportunity there for people to trade normally, there is an opportunity for people to socialise.
"If the public health advice is such, it's the same today as it will be tomorrow - as it will be on Monday.
"So the sooner the better for those businesses that have been significantly impacted now for a full 22 months".