Irish people's trust in vaccines is below the global average, but above the level recorded in western Europe.
A major report by the Wellcome Trust looked at over 140 countries, and found 79% of people think vaccines are safe.
The level of trust in vaccinations is at 74% in Ireland - with 51% saying they strongly agree vaccines are safe and a further 23% saying they somewhat agree.
93% of respondents who are parents said their children have received a vaccine.
However, the Irish level of trust in vaccines is higher than many other countries - with just 59% in western Europe overall agreeing that vaccines are safe, with that percentage falling to 50% for eastern Europe.
In France, one in three people disagreed that vaccines are safe - the highest number recorded in any country.
Trust in vaccines is highest in south Asia (95%) and eastern Africa (92%).
Globally, 79% of people somewhat or strongly agree that vaccines are safe - with 7% somewhat or strongly disagreeing.
Overall, the study shows that in high-income regions there is less certainty about the safety of vaccines.
However, 92% of parents worldwide said that their children have received a vaccine.
The study suggests public mistrust in vaccines has led to a step backwards in fighting deadly but preventable infectious diseases.
It notes that a decision not to vaccinate is "not just a personal choice of risk-taking... it also poses a risk to others".
Speaking about the results, Jeremy Farrar, director of Wellcome, observed: "No matter how great your idea, how exciting your new treatment, or how robust your science, it must be accepted by the people who stand to benefit from it.
"Vaccines, for example, are one of our most powerful public health tools, and we need people to have confidence in them if they are to be most effective."