A lottery ticket sold in Tennessee had the winning numbers for a $421 million Powerball jackpot.
Reuters reports that no one as yet has claimed the prize, which has been rolling over since September 17th.
The jackpot rose from $403 million to a reported $420.9 million due to a flurry of late ticket-buying last night.
The prize is paid out over 30 years, with the option of a lump sum payment, which officials said would add up to about $254.7 million.
The odds of winning the Powerball jackpot are 1 in 292 million.
The largest ever US lottery prize of $1.6 billion was split between three winning tickets in January this year.
Powerball is played in 44 states, as well as Columbia and Puerto Rico.