Now, when it comes to the obesity crisis facing many developed nations all across the world it can be easy to be reductive about it.

“Just eat less” or “ just cut out the junk” or something like that. But what if there was something going on inside your brain that meant you never felt satisfied?

What if you felt hungry all the time no matter how much you ate? How could we fight such a primal urge?

Dr Moran Shalev-Benami, from the Department of Chemical & Structural Biology & Principal Investigator at the Weizmann Institute of Science in Israel joined Jonathan to discuss