Manchester City have confirmed that Riyad Mahrez and Aymeric Laporte have both tested positive for COVID-19.
City say neither player was displaying symptoms of the virus but both players will not be allowed to train with Pep Guardiola's squad as they self-isolate in line with UK government and Premier League rules.
City lost home and away to Wolves last season with Guardiola's side finishing 18 points behind champions Liverpool.
A club statement read: "Manchester City FC can confirm that Riyad Mahrez and Aymeric Laporte have tested positive for Covid-19.
"Both players are currently observing a period of self-isolation in accordance with Premier League and UK Government protocol on quarantine. Neither is displaying symptoms of the virus.
"Everyone at the Club wishes Riyad and Aymeric a speedy recovery ahead of their return to training and the new season."