League leaders Man United host bitter rivals Liverpool at 1.30pm.
United start with Robin Van Persie and Danny Wellbeck up front while Daniel Sturridge is on the bench for Liverpool.
The Merseysiders go into the game, 21 points behind United but manager Brendan Rodgers says it does not get much bigger than this:
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A win for United would move them 10 points clear of Manchester City for a few hours at least.
City are at the Emirates to take on Arsenal at 4.00.